GHRH-A2 (Sermorelin) (10mg)
$139.00
GHRH-A2 is a synthetic peptide analog that binds to pituitary receptors. Research applications involve the observation of growth hormone production and release cycles. It is frequently used in studies requiring the maintenance of natural feedback mechanisms within the endocrine system.
Availability: In Stock
Description
Description
Sermorelin (GHRH-A2)
SAVE OVER 70%
MANUFACTURER ID: WF03
BATCH ID: SM20250723
✓ HPLC PURITY: 99.84%
| Cost per Milligram | $4.15 – $5.70 |
|---|---|
| Endotoxin Status | Certified Endotoxin-Safe |
| Molecular Profile | Synthetic GHRH Analog (29 Amino Acids) |
| Independent Validation | Yes - Verified & Tested |
Scientific Research Monographs // Educational Use Only
Inhibition of Glioma Cell Proliferation
Source: PMC (2021)
Scientific Findings
Research on glioma cell lines (U87/LN229) demonstrated that Sermorelin inhibits proliferation in a dose-dependent manner. Mechanism of action involves cell cycle blockade. Analyses showed a negative correlation between Drug Resistance Scores (DRS) and cell proliferation, alongside potential immune function modulation.
Plain English Interpretation
Scientists tested Sermorelin on brain tumor cells in a lab and found it could stop them from multiplying. The study suggests the peptide works by "jamming" the cancer cells' internal clock so they can't divide, while potentially helping the immune system recognize the threat.
Metabolic Degradation & Plasma Stability
Source: LC-HRMS/MS Analytical Science
Scientific Findings
In vitro incubation in human plasma revealed that Sermorelin is completely degraded within 4 hours. The primary metabolite identified was GRF(3-29), resulting from N-terminal cleavage by the enzyme dipeptidyl peptidase-IV (DPP-IV).
Plain English Interpretation
Researchers looked at how quickly Sermorelin breaks down in the blood. They found that a specific enzyme acts like "molecular scissors," cutting the peptide into a smaller piece called a metabolite. Identifying this piece is essential for scientists to track how the peptide travels through the body.
Detection of Synthetic GHRH Analogs
Source: Wiley Online Library
Scientific Findings
Studies investigating the in vitro metabolism of GHRH analogs identified nineteen major metabolites. For Sermorelin, identifying these degradation products is vital for establishing detection limits in urine and understanding the substance's stability in various biological enzyme systems.
Plain English Interpretation
This research mapped out nearly 20 different ways Sermorelin can break down in biological fluids. This mapping helps laboratory scientists build highly sensitive tests to find even tiny traces of the peptide or its "footprints" in research samples.
RESEARCH NOTICE: For laboratory research and development only. Not for human consumption. Reference: AP-SERM-2026.
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Storage Details
Stability & Storage Protocol
DOC ID: AP-STB-2026
Advanced Lyophilization Process
At Accel Peptides, we partner with manufacturing facilities specializing in Lyophilization (freeze-drying). This advanced process ensures compounds remain stable during transit and storage for over 12 months.When kept in their freeze-dried state, these compounds stay effective for extended periods. For long-term preservation, we recommend storing them in the freezer to maintain maximum molecular integrity.
FDA Standard Requirement
The common "discard 28 days after first use" guideline is a standard requirement set for multi-use vials to confirm bacteriostatic water retains its preservative qualities.
Accel Empirical Experience
With strict sterile handling and refrigeration, a reconstituted vial can safely remain stable and effective for three months or longer.
*Stability is dependent on sterile technique and consistent temperature control.
Certificates of Analysis
13 Peptide COAs
Avg purity —%
Lab: Freedom Diagnostics
| Peptide / Blend | Batch / Product Lot | Accession No. | Reported Date | Purity (HPLC-MS) | Laboratory | Certificate |
|---|
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