MC-A1 (PT-141) (10mg)
$139.00
MC-A1 is a melanocortin receptor agonist. Its research profile focuses on central nervous system interactions, specifically the activation of brain pathways related to arousal responses and neural signaling, independent of vascular mechanisms.
Availability: In Stock
Description
Description
PT-141 (Bremelanotide)
SAVE OVER 40%
MANUFACTURER ID: VI32
BATCH ID: PT202512
✓ HPLC PURITY: 99.89%
| Cost per Milligram | $3.20 – $4.20 |
|---|---|
| Chemical Structure | Synthetic Heptapeptide / MT-II Derivative |
| Endotoxin-Safe | Yes (Certified) |
| Independent Validation | Yes - Verified |
Scientific Research Monographs // Educational Use Only
Mechanism of Melanocortin Receptor Activation
Source: Current Topics in Medicinal Chemistry
Scientific Findings
PT-141 demonstrates strong binding affinity for MC1R, MC3R, and MC4R. In vitro studies using HEK-293 cells show that PT-141 acts as a potent agonist, triggering the cAMP signaling pathway—a key secondary messenger for G-protein coupled receptor activation.
Plain English Interpretation
This research confirms that PT-141 acts as a "key" that fits into specific "locks" (receptors) on cell surfaces. Once attached, it triggers a chain reaction that produces a chemical messenger (cAMP) responsible for controlling sexual function.
Glioblastoma Growth Inhibition via Survivin Suppression
Source: Anticancer Research (Sept 2024)
Scientific Findings
Bremelanotide was found to induce cell death in human glioblastoma lines by reducing the expression of survivin, an anti-apoptotic protein. This effect was receptor-mediated and enhanced the efficacy of standard chemotherapeutic agents like temozolomide.
Plain English Interpretation
In lab tests, this compound helped kill brain cancer cells by stripping away their "shield" (a protein called survivin). It did this without hurting healthy cells and even made traditional chemotherapy more effective.
Cryo-EM Visualization of MC4R Activation
Source: Cell Research / Nature
Scientific Findings
Single-particle cryo-electron microscopy allowed visualization of the bremelanotide-MC4R-Gs complex at 3.1 Å resolution. This revealed the precise binding mode of the peptidic agonist, providing molecular details for receptor subtype selectivity.
Plain English Interpretation
Scientists used ultra-powerful microscopes to see the drug attached to the receptor at near-atomic levels. This "blueprint" shows exactly how the drug binds, helping researchers understand why it is so effective and selective.
RESEARCH NOTICE: For laboratory research and development only. Not for human consumption. Reference: AP-PT141-2026.
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Storage Details
Stability & Storage Protocol
DOC ID: AP-STB-2026
Advanced Lyophilization Process
At Accel Peptides, we partner with manufacturing facilities specializing in Lyophilization (freeze-drying). This advanced process ensures compounds remain stable during transit and storage for over 12 months.When kept in their freeze-dried state, these compounds stay effective for extended periods. For long-term preservation, we recommend storing them in the freezer to maintain maximum molecular integrity.
FDA Standard Requirement
The common "discard 28 days after first use" guideline is a standard requirement set for multi-use vials to confirm bacteriostatic water retains its preservative qualities.
Accel Empirical Experience
With strict sterile handling and refrigeration, a reconstituted vial can safely remain stable and effective for three months or longer.
*Stability is dependent on sterile technique and consistent temperature control.
Certificates of Analysis
13 Peptide COAs
Avg purity —%
Lab: Freedom Diagnostics
| Peptide / Blend | Batch / Product Lot | Accession No. | Reported Date | Purity (HPLC-MS) | Laboratory | Certificate |
|---|
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